Publications

Ammanamanchi N, Yester J, Bargaje AP, Thomas D, Little KC, Janzef S, Francis K, Weinberg J, Johnson J, Seery T et al..  2024.  Elimination of 15N-thymidine after oral administration in human infants.. PLoS One. 19(1):e0295651.

Li Y, Bertozzi A, Mann MRw, Kühn B.  2023.  Interdependent changes of nuclear lamins, nuclear pore complexes, and ploidy regulate cellular regeneration and stress response in the heart.. Nucleus. 14(1):2246310.

Mich-Basso JD, Kühn B.  2023.  Protocol to image and quantify nuclear pore complexes using high-resolution laser scanning confocal microscopy.. STAR Protoc. 4(3):102552.

Han L, Mich-Basso JD, Li Y, Ammanamanchi N, Xu J, Bargaje AP, Liu H, Wu L, Jeong J-H, Franks J et al..  2022.  Changes in nuclear pore numbers control nuclear import and stress response of mouse hearts.. Dev Cell. 57(20):2397-2411.e9.

Auchampach J, Han L, Huang GN, Kühn B, Lough JW, O'Meara CC, Payumo AY, Rosenthal NA, Sucov HM, Yutzey KE et al..  2022.  Measuring cardiomyocyte cell-cycle activity and proliferation in the age of heart regeneration.. Am J Physiol Heart Circ Physiol. 322(4):H579-H596.

Khoudary SREl, Fabio A, Yester JW, Steinhauser ML, Christopher AB, Gyngard F, Adams PS, Morell VO, Viegas M, Da Silva JP et al..  2021.  Design and rationale of a clinical trial to increase cardiomyocyte division in infants with tetralogy of Fallot.. Int J Cardiol. 339:36-42.

Han L, Mich-Basso J, Kühn B.  2021.  Generation of Human Induced Pluripotent Stem Cells and Differentiation into Cardiomyocytes.. Methods Mol Biol. 2158:125-139.

Liu H, Bersell K, Kühn B.  2021.  Isolation and Characterization of Intact Cardiomyocytes from Frozen and Fresh Human Myocardium and Mouse Hearts.. Methods Mol Biol. 2158:199-210.

Kirillova A, Han L, Liu H, Kühn B.  2021.  Polyploid cardiomyocytes: implications for heart regeneration.. Development. 148(14)

Yester JW, Liu H, Gyngard F, Ammanamanchi N, Little KC, Thomas D, Sullivan MLG, Lal S, Steinhauser ML, Kühn B.  2021.  Use of stable isotope-tagged thymidine and multi-isotope imaging mass spectrometry (MIMS) for quantification of human cardiomyocyte division.. Nat Protoc. 16(4):1995-2022.

Han L, Choudhury S, Mich-Basso JD, Ammanamanchi N, Ganapathy B, Suresh S, Khaladkar M, Singh J, Maehr R, Zuppo DA et al..  2020.  Lamin B2 Levels Regulate Polyploidization of Cardiomyocyte Nuclei and Myocardial Regeneration.. Dev Cell. 53(1):42-59.e11.

Liu H, Zhang C-H, Ammanamanchi N, Suresh S, Lewarchik C, Rao K, Uys GM, Han L, Abrial M, Yimlamai D et al..  2019.  Control of cytokinesis by β-adrenergic receptors indicates an approach for regulating cardiomyocyte endowment.. Sci Transl Med. 11(513)

Lal S, Kühn B.  2019.  Regenerating Hearts by Arresting Development With Hypothyroidism.. Circ Res. 124(12):1725-1726.

Missinato MA, Saydmohammed M, Zuppo DA, Rao KS, Opie GW, Kühn B, Tsang M.  2018.  Dusp6 attenuates Ras/MAPK signaling to limit zebrafish heart regeneration.. Development. 145(5)

Gong Z, Tasset I, Diaz A, Anguiano J, Tas E, Cui L, Kuliawat R, Liu H, Kühn B, Cuervo AMaria et al..  2018.  Humanin is an endogenous activator of chaperone-mediated autophagy.. J Cell Biol. 217(2):635-647.

Yester JWettig, Kühn B.  2017.  Mechanisms of Cardiomyocyte Proliferation and Differentiation in Development and Regeneration.. Curr Cardiol Rep. 19(2):13.

Polizzotti BD, Ganapathy B, Haubner BJ, Penninger JM, Kühn B.  2016.  A cryoinjury model in neonatal mice for cardiac translational and regeneration research.. Nat Protoc. 11(3):542-52.

Liu H, Qin W, Wang Z, Shao Y, Wang J, Borg TK, Gao BZ, Xu M.  2016.  Disassembly of myofibrils and potential imbalanced forces on Z-discs in cultured adult cardiomyocytes.. Cytoskeleton (Hoboken). 73(5):246-57.

Ganapathy B, Nandhagopal N, Polizzotti BD, Bennett D, Asan A, Wu Y, Kühn B.  2016.  Neuregulin-1 Administration Protocols Sufficient for Stimulating Cardiac Regeneration in Young Mice Do Not Induce Somatic, Organ, or Neoplastic Growth.. PLoS One. 11(5):e0155456.

Dueck H, Khaladkar M, Kim TKyung, Spaethling JM, Francis C, Suresh S, Fisher SA, Seale P, Beck SG, Bartfai T et al..  2015.  Deep sequencing reveals cell-type-specific patterns of single-cell transcriptome variation.. Genome Biol. 16(1):122.

Yang H, Borg TK, Liu H, Gao BZ.  2015.  Interactive relationship between basement-membrane development and sarcomerogenesis in single cardiomyocytes.. Exp Cell Res. 330(1):222-32.

Polizzotti BD, Ganapathy B, Walsh S, Choudhury S, Ammanamanchi N, Bennett DG, Remedios CGDos, Haubner BJ, Penninger JM, Kühn B.  2015.  Neuregulin stimulation of cardiomyocyte regeneration in mice and human myocardium reveals a therapeutic window.. Sci Transl Med. 7(281):281ra45.

Senyo SE, Lee RT, Kühn B.  2014.  Cardiac regeneration based on mechanisms of cardiomyocyte proliferation and differentiation.. Stem Cell Res. 13(3 Pt B):532-41.

Liu H, Chen R, Yang H, Qin W, Borg TK, Dean D, Xu M, Gao BZ.  2014.  Enzyme-etching technique to fabricate micropatterns of aligned collagen fibrils.. Biotechnol Lett. 36(6):1245-52.

Zhang C-H, Kühn B.  2014.  Muscling up the heart: a preadolescent cardiomyocyte proliferation contributes to heart growth.. Circ Res. 115(8):690-2.