Submitted by nia4019 on February 5, 2024 - 2:05pm
| Title | Muscling up the heart: a preadolescent cardiomyocyte proliferation contributes to heart growth. |
| Publication Type | Journal Article |
| Year of Publication | 2014 |
| Authors | Zhang C-H, Kühn B |
| Journal | Circ Res |
| Volume | 115 |
| Issue | 8 |
| Pagination | 690-2 |
| Date Published | 2014 Sep 26 |
| ISSN | 1524-4571 |
| Keywords | Animals, Cell Differentiation, Cell Proliferation, Heart, Male, Myocytes, Cardiac |
| Abstract | A recent study from Naqvi et al in Cell shows that in mice during preadolescence, cardiomyocytes undergo a burst of proliferation that is related to a thyroid hormone surge. This study challenges the conventional model of the timing of terminal differentiation and provides a direction for further mechanistic research on cardiomyocyte proliferation and differentiation. |
| DOI | 10.1161/CIRCRESAHA.114.304632 |
| Alternate Journal | Circ Res |
| PubMed ID | 25258401 |
| PubMed Central ID | PMC4196263 |
| Grant List | K08 HL085143 / HL / NHLBI NIH HHS / United States R01 HL106302 / HL / NHLBI NIH HHS / United States U01 MH098953 / MH / NIMH NIH HHS / United States R01HL106302 / HL / NHLBI NIH HHS / United States |